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Clostridium difficile GDH + Toxin A/B Kombi

Clostridium difficile GDH + Toxin A/B Kombi2020-07-14T10:42:39+02:00

Rapid test for Clostridioides difficile
GDH and Toxin A/B combination in a double cartridge!

Clostridioides difficile (formerly: Clostridium difficile) associated diseases (CDAD) are the most frequently identified causes of nosocomial diarrhoea and the most important diarrhoeal disease of inpatients in Germany. The BIOMED combined test enables the identification of GDH (glutamate dehydrogenase), toxin A and B in one step.
According to § 6 paragraph 1 No. 5a IfSG C. difficile must be reported to the public health department for severe cases of illness and for all infections caused by the ribotypes 027 and 078.

Advantages of the combined rapid test:
  • Easy and safe test handling

  • Testing of several factors simultaneously

  • Rapid assessment using the one-step immunochromatic rapid test

  • Rapid containment of disease outbreaks by reducing the risk of infection

  • Reliable exclusion of CDAD

  • Ready-to-use test kit with all necessary materials

  • Test result visible after 15 minutes

  • Targeted therapy for improved patient care

Performance data
PathogensSensitivitySpecificityRepeatability
GDH95,0 %99,0 %100 %
Toxine A and B94,6 %> 99,9 %100 %

Clostridioides difficile

Clostridioides difficile associated diseases (CDAD) are the most frequently identified causes of nosocomial diarrhoea and the most important diarrhoeal disease of inpatients (about 20 to 40 % of hospital patients are colonized with C. difficile) in Germany.
Clostridioides difficile is a spore- and toxin-forming Gram-positive rod bacterium, which is one of the bacteria found in the intestinal flora of 3% of healthy adults. It is much more common in infants, but rarely causes problems.
The outbreak of a disease or proliferation of the bacterium is usually the result of a disturbance of the intestinal flora, whether through antibiotic treatment, colonoscopy or other interventions, by which competing types of normal intestinal colonisation are suppressed. As a consequence of this altered intestinal flora, C. difficile can proliferate and produce and release toxins (toxins A and B) that damage the intestinal wall, causing infectious diarrhoea (Clostridioides difficile infection, abbreviation CDI) and possibly leading to life-threatening pseudomembranous colitis.
The bacterium with high environmental resistance (spores insensitive to heat and many disinfectants) is transmissible from person to person. Over 80% of the reported diseases occur in the older generation (> 65 years).

C. Diff Rapid Test GDH

POC-Diagnostics

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