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Rotavirus – Adenovirus – Norovirus

Rotavirus – Adenovirus – Norovirus2020-07-14T09:00:04+02:00

3-in-1 rapid diagnostic test for Rota-, Adeno- and Norovirus in one cartridge!

The most common cause of violent vomiting and diarrhoea is viral gastroenteritis, caused mainly by noroviruses, adenoviruses or rotaviruses. Seen globally, diarrhoeal diseases are the second most common cause of death after cardiovascular diseases.
According to § 7 para. 1 IfSG the direct or indirect detection of rota- and norovirus, if it indicates an acute infection, must be reported to the public health department.

Rota-Adeno-Noro-Schnelltest

Benefit of the 3-in-1 rapid diagnostic test:
  • Simple and safe test handling

  • Rapid containment of diarrhoeal diseases

  • Diagnosis of solid and liquid stool
  • Start immediately with ready-to-use test kit for sample preparation
  • Only one sample for the simultaneous detection of three viruses
  • Quick test result after 15 minutes
  • Can be invoiced according to GÖA and EBM

Performance data
PathogenSensitivitySpecificity
Rotavirus>99.9%>98.8%
Adenovirus>99.9%>97.6%
Norovirus GI87.5%98.9%
Norovirus GII95.0%96.6%

Common pathogens of gastroenteritis:
Rotavirus is a double-stranded RNA virus from the Reoviridae family. These are viruses with a low infectious dose, the transmission mechanism of which is direct contact between one person and another via the faecal-oral route and less frequently via contaminated water and food. Rotavirus is one of the most important agents of acute gastroenteritis in the world and is the main cause of severe dehydration in children aged between 6 months and 2 years, both in developing countries where it has a high mortality rate, as well as in developed countries. At the age of 5 years >95% of children have suffered at least once from gastroenteritis caused by rotavirus. Although the development of vaccines helps to reduce the incidence, only some countries have used them in their national immunisation programme. Rotavirus is divided into seven serogroups (A to G). Only groups A, B and C are infectious to humans, with group A being the most common.
Adenovirus is the third most common cause of viral gastroenteritis in children (10-15%); it can also cause respiratory diseases and, depending on the serotype, diarrhoea, conjunctivitis, cystitis and others. At least 47 adenovirus serotypes have been identified and the hexon antigen is present in all of them. Serotypes 40 and 41 are associated with gastroenteritis. The most important clinical symptom of adenoviral-induced gastroenteritis is diarrhoea, which can occur for 9 to 12 days, even in combination with fever and vomiting.
Norovirus is a type of single-stranded RNA virus with positive polarity of the Caliciviridae family. It is highly contagious and the main transmission routes are personal contact and contaminated food/water. The virus usually causes violent epidemics in closed groups (hospitals, nursing homes, schools, kindergartens, restaurants, cruise ships, etc.), where the infection spreads very quickly after its introduction. Several studies have shown that norovirus is the leading cause of viral gastroenteritis of all ages worldwide and is responsible for almost 50% of gastroenteritis outbreaks. Noroviruses are grouped into five genogroups (GI to GM), and within each genogroup the virus is divided into genotypes. The majority of clinical cases are the result of strains of genogroups I and II, with the genotypes GI.1 and GII.4 being the most common. In general, GI infections are less frequent than GII infections.

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