Rotavirus and Adenovirus: One step rapid test

The classic combitest:
quick test for Rota- and Adenovirus in one cartridge!

Rotavirus and adenovirus are the two most common causes of transmissible viral gastroenteritis in infants and young children.
An infection with the rota or adenovirus is the most likely cause of hospitalization due to a gastrointestinal infection.
According to § 7 para. 1 IfSG the direct or indirect detection of rotavirus, if it indicates an acute infection, must be reported to the public health department.

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Advantages of the combination test:

Easy and safe handling
Rapid containment of disease outbreaks
Diagnosis of solid and liquid stool
Ready-to-use test kit with all necessary materials
Only one sampling for the simultaneous detection of both viruses
Test result visible after 10 minutes
Can be invoiced according to GÖA and EBM

Performance data

Pathogen	Sensitivity	Specificity
Rotavirus	>99%	>98%
Adenovirus	>99%	>99%

Common pathogens of gastroenteritis:

Rotavirus

Rotavirus is a double-stranded RNA virus from the Reoviridae family. These are viruses with a low infectious dose, the transmission mechanism of which is direct contact between one person and another via the faecal-oral route and less frequently via contaminated water and food. Rotavirus is one of the most important agents of acute gastroenteritis in the world and is the main cause of severe dehydration in children aged between 6 months and 2 years, both in developing countries where it has a high mortality rate, as well as in developed countries. At the age of 5 years >95% of children have suffered at least once from gastroenteritis caused by rotavirus. Although the development of vaccines helps to reduce the incidence, only some countries have used them in their national immunisation programme. Rotavirus is divided into seven serogroups (A to G). Only groups A, B and C are infectious to humans, with group A being the most common.

Adenovirus

Adenovirus is the third most common cause of viral gastroenteritis in children (10-15%); it can also cause respiratory diseases and, depending on the serotype, diarrhoea, conjunctivitis, cystitis and others. At least 47 adenovirus serotypes have been identified and the hexon antigen is present in all of them. Serotypes 40 and 41 are associated with gastroenteritis. The most important clinical symptom of adenoviral-induced gastroenteritis is diarrhoea, which can occur for 9 to 12 days, even in combination with fever and vomiting.