The acute-phase protein C-reactive protein (CRP) is a pentraxin. It is part of the body’s own defense system and it is produced in the liver. Acute phase proteins are defined as proteins whose blood concentration increases as a result of inflammatory reactions. The CRP is a non-specific inflammation marker, the concentration of CRP in the blood can be used to determine the severity, but not the type of inflammatory disease. After the inflammation subsides, the CRP level rapidly decrease to normal.