CRP Controls: Quality control for C-reactive protein
The acute-phase protein C-reactive protein (CRP) is a pentraxin. It is part of the body’s own defense system and it is produced in the liver. Acute phase proteins are defined as proteins whose blood concentration increases as a result of inflammatory reactions. The CRP is a non-specific inflammation marker, the concentration of CRP in the blood can be used to determine the severity, but not the type of inflammatory disease. After the inflammation subsides, the CRP level rapidly decrease to normal.
CRP controls: Control sera for the early inflammatory response
The CRP controls are trueness controls for C-reactive protein. They are stable human serum-based liquid controls used to monitor analytical conditions in CRP determinations. CRP Controls Duotrol® CRP-Qualitätskontrollen are available in seven different concentration ranges (7 levels) to provide an accurate estimate of an individual patient’s increase in CRP concentration. In the context of acute inflammation, CRP in the blood usually increases 10- to 100-fold within a few hours, depending on the severity of the inflammation. The most significant increase occurs in bacterial infections. In chronic inflammations, there is a permanent, less pronounced activation of CRP.
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