Clostridium difficile GDH + Toxin A/B test

Clostridium difficile GDH + Toxin A/B test2023-02-25T11:38:26+01:00

Clostridioides difficile GDH + Toxin A/B test in a double cassette!

Clostridioides difficile (formerly: Clostridium difficile) associated diseases (CDAD) are the most frequently identified causes of nosocomial diarrhoea and the most important diarrhoeal disease of inpatients in Germany. The BIOMED combined test enables the identification of GDH (glutamate dehydrogenase), toxin A and B in one step.
According to § 6 paragraph 1 No. 5a IfSG C. difficile must be reported to the public health department for severe cases of illness and for all infections caused by the ribotypes 027 and 078.

Advantages Clostridioides difficile GDH + Toxin A/B Test:
  • Easy and safe test handling

  • Testing of several factors simultaneously
  • Rapid assessment using the one-step immunochromatic rapid test
  • Rapid containment of disease outbreaks by reducing the risk of infection
  • Reliable exclusion of CDAD
  • Ready-to-use test kit with all necessary materials

  • Test result visible after 15 minutes
  • Targeted therapy for improved patient care

Performance data

GDH95,0 %99,0 %100 %
Toxine A and B94,6 %> 99,9 %100 %

Clostridioides difficile

Clostridioides difficile associated diseases (CDAD) are the most frequently identified causes of nosocomial diarrhea and the most significant diarrheal disease of hospitalized patients (approximately 20 to 40% of hospitalized patients are colonized with C. difficile) in Germany.
Clostridioides difficile is a spore- and toxin-forming gram-positive rod bacterium, which is one of the bacteria found in the intestinal flora of 3% of healthy adults. It is far more common in infants, but rarely causes problems.
The onset of disease or proliferation of the bacterium is usually the result of a disruption of the intestinal flora, whether by antibiotic treatment, colonoscopy, or other interventions that push back competing species of normal intestinal colonization. As a result of this altered intestinal flora, C. difficile can proliferate and produce and release intestinal wall-damaging toxins (toxins A and B) that can cause infectious diarrheal disease (Clostridioides difficile infection, abbreviated CDI) and possibly lead to life-threatening pseudomembranous colitis.
The bacterium with high environmental resistance (spores insensitive to heat and many disinfectants) is transmissible from person to person. Over 80% of reported cases occur in the older generation (> 65 years).

C. Diff Rapid Test GDH


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