Protein quality controls
In protein diagnostics, blood plasma proteins, also known as plasma proteins, which circulate between the blood and extracellular fluid spaces, are analysed. Plasma proteins are mainly produced in the liver and in the lymphatic organs of the immune system. Under physiological conditions more than 100 known proteins are present in the blood in constant distribution between the fluid spaces.
Plasma proteins can be divided into different groups according to their function:
Transport proteins are proteins that specifically enable or facilitate the transport of a substance. The destination of the transported factor can be inside or outside the same cell or elsewhere in a multicellular organism. Transport proteins are often stationary in the cell membrane and enable passive or active transport through the cell membrane.
As a result of tissue damage, acute-phase proteins are secreted into the blood as part of the unspecific immune reaction (acute-phase reaction). Their tasks are the localisation of the inflammation, the prevention of its spread and the support of the immune system in the rehabilitation of the focus of inflammation.
The C-reactive protein (CRP) is used to assess the severity of inflammatory reactions, as the blood concentration increases with inflammation (non-infectious: tissue damage, infectious: microbial infection).
Proteins of the immune defence
The body’s immune system is composed of mechanical barriers (e.g. skin), cellular (e.g. granulocytes) and humoral (liquid) components. The humoral part of the immune system includes various plasma proteins that circulate in the blood and other body fluids.
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Duotrol® quality controls
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